Fluid bed equipment has been established in the pharmaceutical industry for more than 50 years. Today, fluid bed drying can still be considered state of the art within pharmaceutical processes. One technology is the bottom spray setup, whereby the spray nozzles were placed at the bottom of the apparatus. Herewith coating of tablets with an additional insert was possible. This type has been used for decades in the pharmaceutical industry. The most promising change was the development of the fluid beds with tangentially mounted nozzles.
This method is now considered state of the art for several reasons:
Compared to classic designs, tangential fluid beds offer drying, granulation and coating in one device without any modification or additional inserts.
As the wet particles, granules or small tablets move in a tangential manner with quite a low level of fluid, a high expansion volume is not needed as before with the classic top spray equipment. This scenario significantly reduces the installation height of this equipment and needs less production space, thereby presenting cost saving opportunities.
Another advantage is the specially slotted air distributor plate with a conical displacement cone. This feature creates a complete particle fluidization which guarantees high coating uniformity without particle twinning issues.
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